Author

Lorenzo Landini

University of FlorenceORCID 0000-0002-3933-2497Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Elisa Bellantoni· 2 shared Francesco De LoguiD· 2 shared Gaetano De SienaiD· 2 shared Irene ScuffiiD· 2 shared Marco MontiniiD· 2 shared Martina ChiecaiD· 2 shared Matilde MariniiD· 2 shared Romina NassiniiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersGenetics

Elisa Bellantoni

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2 papers

Recent·Most cited

Disentangling Schwann Cell and Neuronal TRPA1 Function in Mouse Models of Familial Episodic Pain Syndrome

Matilde Marini, Martina Chieca, Elisabetta Coppi, Marco Montini, Lorenzo Bonacchi, Lorenzo Landini, Irene Scuffi, Kelvin Y. Kwan, Alice Papini, Gaetano De Siena, Elisa Bellantoni, Lucrezia Timotei, Valentina Albanese, Gabriele Ferroni, Evelynn Dalila do Nascimento Melo, , Francesco De Logu

This study investigates the cell-specific roles of mutant TRPA1 in FEPS using mouse models, showing distinct contributions of neuronal and Schwann cell TRPA1 to pain mechanisms.

bioRxiv · Feb 17, 2026 · PreprintGenetics

Targeting the Schwann Cell EP2/cAMP Nanodomain to Block Pain but not Inflammation

Romina Nassini, Lorenzo Landini, Matilde Marini, Martina Chieca, Daniel Souza Monteiro de Araújo, Marco Montini, Pasquale Pensieri, Vittorio Abruzzese, Gaetano De Siena, Jin Zhang, Elisa Bellantoni, Vincenzo DE GIORGI, Antonia Romitelli, Giulia Brancolini, Raquel Tonello, , Pierangelo Geppetti

The paper identifies a druggable EP2 receptor in Schwann cells that encodes PG-mediated persistent inflammatory pain without affecting protective inflammation.

Nature Communications · Sep 25, 2025Peer-reviewedPharmacology & Toxicology