Author

Andrea Hildebrandt

Institute of Molecular BiologyPrimary ORCID profile (0000-0001-5564-0126 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Andrea HildebrandtiD3 papers · Carl von Ossietzky Universität Oldenburg

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Julian KönigiD· 3 shared Anke BuschiD· 2 shared Annabelle DoldiD· 2 shared Cornelia RückléiD· 2 shared Heike Hänel· 2 shared Jean‐Yves RoignantiD· 2 shared Kathi ZarnackiD· 2 shared Mirko BrüggemanniD· 2 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Julian KönigORCID

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3 papers

Recent·Most cited

Makorin1 controls embryonic patterning by alleviating Bruno-mediated repression of oskar translation

Annabelle Dold, Hong Ryul Han, Niankun Liu, Andrea Hildebrandt, Mirko Brüggemann, Cornelia Rücklé, Heike Hänel, Anke Busch, Petra Beli, Kathi Zarnack, Julian König, Jean‐Yves Roignant, Paul F. Lasko

This study shows that Makorin1 promotes oskar translation by displacing Bruno from its 3' UTR, essential for embryonic patterning and germ cell formation in Drosophila.

PLoS Genetics · Jan 24, 2020Peer-reviewedDevelopmental Biology

The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A)-translation

Andrea Hildebrandt, Mirko Brüggemann, Cornelia Rücklé, Susan Boerner, Jan B. Heidelberger, Anke Busch, Heike Hänel, Andrea Voigt, Martin M. Möckel, Stefanie Ebersberger, Anica Scholz, Annabelle Dold, Tobias Schmid, Ingo Ebersberger, Jean‐Yves Roignant, , Petra Beli

This study identifies MKRN1 as a key player in ribosome-associated quality control by promoting ribosome stalling at poly(A) sequences to prevent erroneous protein production.

Genome biology · Oct 22, 2019Peer-reviewedMolecular Biology

GTSF-1 is required for the formation of a functional RNA-dependent RNA Polymerase complex in C. elegans

Miguel Vasconcelos Almeida, Sabrina Dietz, Stefan Redl, Emil Karaulanov, Andrea Hildebrandt, Christian Renz, Helle D. Ulrich, Julian König, Falk Butter, René F. Ketting

The paper identifies GTSF-1 as a protein required for the formation of an RNA-dependent RNA Polymerase complex in C. elegans, which is essential for 26G-RNA generation.

The EMBO Journal · May 16, 2018Peer-reviewedMolecular Biology