Toshihiko Yada

Gut-derived GLP-1 released by rare sugar D-allulose cooperates with insulin to activate left-sided vagal afferents and enhance insulin sensitivity

This paper shows that D-allulose-induced GLP-1 enhances insulin action via left-sided vagal afferents, improving glucose tolerance more effectively than GLP-1 receptor agonists in mice.

Exacerbation of sucrose-induced visceral obesity and glucose intolerance by ovariectomy and its GLP-1-dependent amelioration by the rare sugar D-allulose

This study shows that D-allulose reduces visceral obesity and glucose intolerance in ovariectomized mice, with effects dependent on GLP-1.

A skeletal muscle-sympathetic nerve-intestine network underlies muscle inflammation and atrophy induced by immobilization

This study identifies a muscle-sympathetic nerve-intestine network that drives inflammation and atrophy in immobilized muscles, showing that intestinal inflammation contributes to muscle damage.