Jennifer Geddes‐McAlister

The paper maps virulence-associated protein interaction networks in Cryptococcus neoformans to identify regulators of thermotolerance, revealing two novel proteins involved in heat-shock protein interactions.

This study identifies fungal proteins involved in immune system remodeling and immunization potential using a combined proteomics and phenotyping approach in Cryptococcus neoformans.

This study evaluates adaptive focused acoustics (AFA) technology for macrophage lysis and proteomics, showing improved proteome coverage, reproducibility, and detection of low-abundance immune proteins.

This study identifies iron-dependent phosphorylation of TolQ in K. pneumoniae, linking iron availability to Tol-Pal system function and antibiotic susceptibility.

This study identifies SbmA as a regulator of iron homeostasis and antimicrobial susceptibility in K. pneumoniae through phosphorylation-dependent mechanisms, revealing it as a potential therapeutic target.

This study shows that new Fusarium chemotypes reprogram wheat defense networks, altering detoxification and defense responses, and identifies chemotype-specific evasion of host defenses.

The paper designs peptide inhibitors targeting fungal peptidases to reduce virulence and resistance without harming host cells, showing efficacy in vitro and in vivo.

This paper identifies a fungal effector, UmPce3, that targets the chloroplast DEAD-box RNA helicase RH3 to manipulate chloroplast function, enhancing fungal pathogenesis while balancing plant stress responses.

This study examines proteome changes in wheat and Fusarium graminearum in response to 15ADON/3ANX mycotoxins, identifying chemotype-specific proteins and fungal virulence factors.

This study compares proteomic profiles of Cryptococcus neoformans clinical strains to identify differences between latent and lethal infections.

This study uses mass spectrometry to analyze proteome changes in three organs during Cryptococcus neoformans infection, identifying new immune modulatory mechanisms and antifungal targets.

ProteoPlotter is a visualization tool for proteomics data that complements Perseus, offering enhanced features for data analysis and interpretation.

This study identifies AbiV as an RNase in the bacterial antiphage system AbiV, revealing its structure, function, and mechanism of action.