Stephanie N. Samra

Deep nanoparticle protein corona plasma proteomics resolves a stage-specific peripheral signature of Alzheimer's disease

This paper identifies a stage-specific proteomic signature of Alzheimer's disease using plasma proteomics and finds a proteomic switch associated with disease progression.

A structure-guided pipeline yields peptide inhibitors that disarm fungal peptidase-driven virulence and resistance

The paper designs peptide inhibitors targeting fungal peptidases to reduce virulence and resistance without harming host cells, showing efficacy in vitro and in vivo.

Whole blood proteome dynamics defines predictive diagnostic and prognostic signatures of cryptococcal infection

Spatiotemporal dynamics of cryptococcal infection reveal novel immune modulatory mechanisms and antifungal targets

This study uses mass spectrometry to analyze proteome changes in three organs during Cryptococcus neoformans infection, identifying new immune modulatory mechanisms and antifungal targets.