Michael Woods

Systematic Infectome-Phenome Profiling Reveals Cryptococcal Infection-Associated Proteins Driving Immune System Remodeling and Immunization Potential

This study identifies fungal proteins involved in immune system remodeling and immunization potential using a combined proteomics and phenotyping approach in Cryptococcus neoformans.

Adaptive Focused Acoustics-integrated proteome profiling of macrophages uncovers low abundant proteins associated with immune homeostasis, inflammatory response, and transport

This study evaluates adaptive focused acoustics (AFA) technology for macrophage lysis and proteomics, showing improved proteome coverage, reproducibility, and detection of low-abundance immune proteins.

A structure-guided pipeline yields peptide inhibitors that disarm fungal peptidase-driven virulence and resistance

The paper designs peptide inhibitors targeting fungal peptidases to reduce virulence and resistance without harming host cells, showing efficacy in vitro and in vivo.

Whole blood proteome dynamics defines predictive diagnostic and prognostic signatures of cryptococcal infection

Spatiotemporal dynamics of cryptococcal infection reveal novel immune modulatory mechanisms and antifungal targets

This study uses mass spectrometry to analyze proteome changes in three organs during Cryptococcus neoformans infection, identifying new immune modulatory mechanisms and antifungal targets.

Control of fluid flow by Adgrd1 is essential for mammalian oviductal embryo transport

This study shows that Adgrd1 regulates oviductal fluid flow and embryo transport in mice, with its absence causing infertility due to impaired embryo release from the ampullary-isthmic junction.

Establishment In Culture Of Expanded Potential Stem Cells

This paper establishes expanded potential stem cells (EPSCs) from mouse blastomeres and shows they can contribute to both embryo proper and trophoblasts in chimeras.