Günter Fritz

This study identifies PepA as a regulator of nhaB gene expression in Vibrio cholerae, revealing its role in Na+ homeostasis through suppressor mutations in a nhaA nqr mutant.

This study identifies USP24 as a novel ISG15 cross-reactive deubiquitinase that de-ISGylates MOV10 to negatively regulate IFN-I production.

The paper develops a high-throughput synthesis-to-screening method to identify selective USP18 inhibitors from a cyanimide library.

The paper develops a NanoBRET assay to monitor USP18 interactions and identifies a small molecule inhibitor of USP18/ISG15 binding.