Kirill Batmanov

Whole body MondoA deletion protects against diet-induced obesity through uncontrolled multi-organ substrate utilization and futile cycling

This paper shows that deleting MondoA globally protects against diet-induced obesity by increasing energy expenditure through enhanced glucose uptake and glycolytic flux, leading to elevated glycerol synthesis and lipolysis.

Two-hit mouse model of heart failure with preserved ejection fraction combining diet-induced obesity and renin-mediated hypertension

This paper develops a two-hit mouse model of HFpEF combining diet-induced obesity and renin-mediated hypertension, showing key features of the disease and response to therapy.

Defining the lineage of thermogenic perivascular adipose tissue

This study identifies the cellular origins of perivascular adipose tissue using single-cell transcriptomics, fate mapping, and adipogenesis assays, revealing fibroblastic and smooth muscle progenitors.