Author

Jesus F. Barajas

United States Department of EnergyORCID 0000-0002-4910-2222Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 1 Organism:plant (other)· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Jay D. KeaslingiD· 3 shared Edward E. K. BaidooiD· 2 shared Mitchell G. ThompsoniD· 2 shared Pablo Cruz‐MoralesiD· 2 shared Aindrila MukhopadhyayiD· 1 shared Allison N. PearsoniD· 1 shared Bo PangiD· 1 shared Christopher B. EibeniD· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersSynthetic Biology

Jay D. KeaslingORCID

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Author profile →

3 papers

Recent·Most cited

An iron (II) dependent oxygenase performs the last missing step of plant lysine catabolism

Mitchell G. Thompson, Jacquelyn M. Blake-Hedges, Jose Henrique Pereira, John A. Hangasky, Michael S. Belcher, William M. Moore, Jesus F. Barajas, Pablo Cruz‐Morales, Lorenzo J. Washington, Robert W. Haushalter, Christopher B. Eiben, Yuzhong Liu, Will Skyrud, Veronica Teixeira Benites, Tyler P. Barnum, , Jay D. Keasling

The paper identifies an iron-dependent enzyme in plants that completes the lysine catabolism pathway, showing structural and functional conservation across species.

Nature Communications · Jun 10, 2020Peer-reviewedMolecular Biology

Identification, characterization, and application of a highly sensitive lactam biosensor from Pseudomonas putida

Mitchell G. Thompson, Allison N. Pearson, Jesus F. Barajas, Pablo Cruz‐Morales, Nima Sedaghatian, Zak Costello, Megan E. Garber, Matthew R. Incha, Luis E. Valencia, Edward E. K. Baidoo, Héctor García Martín, Aindrila Mukhopadhyay, Jay D. Keasling

The paper develops a highly sensitive biosensor for caprolactam and valerolactam from Pseudomonas putida, capable of detecting product titers above background at ~6 g/L.

ACS Synthetic Biology · Dec 16, 2019Peer-reviewedSynthetic Biology

Evolution-guided engineering of small-molecule biosensors

Tim Snoek, Evan Kirk Chaberski, Francesca Ambri, Stefan Kol, Sara Petersen Bjørn, Bo Pang, Jesus F. Barajas, Ditte Hededam Welner, Michael Krogh Jensen, Jay D. Keasling

This paper describes a method to evolve and functionalize biosensors in yeast by optimizing ligand specificity and transfer functions through directed evolution.

Nucleic Acids Research · Oct 24, 2019Peer-reviewedSynthetic Biology