Author

Saumya Sharma

Institute of Genomics and Integrative BiologyORCID 0000-0002-5227-8616Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Asgar Hussain AnsariiD· 2 shared Debojyoti ChakrabortyiD· 2 shared Deepanjan PauliD· 2 shared Dipanjali Sinha· 2 shared Manoj KumariD· 2 shared Meghali AichiD· 2 shared Mohd. Azhar· 2 shared Namrata Sharma· 2 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Asgar Hussain AnsariORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 7, 2025

Inhibition of PfCLK3 a master regulator of malaria parasite RNA-splicing provides the basis for a radical cure for malaria

Omar Janha, Niniola Olaniyan, Ka Diam Go…·Katarzyna Modrzynska

This study shows that inhibiting PfCLK3 disrupts RNA-splicing in malaria parasites, affecting 1125 genes and providing a novel mechanism for a radical cure.

DOI 10.1101/2025.10.07.680601

bulk RNA-seqstatistical model

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Genetic & Genomic MedicineBiosensors and BioelectronicsPeer-reviewedApr 5, 2021

Rapid, accurate, nucleobase detection using FnCas9

Mohd. Azhar, Rhythm Phutela, Manoj Kumar…·Souvik Maiti

FELUDA uses FnCas9 for rapid, accurate nucleobase detection and is implemented in a point-of-care diagnostic tool for SARS-CoV-2.

240 citationstop 1%

DNA methylationwhole-genome sequencing

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedSep 30, 2019

Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing

Sundaram Acharya, Arpit Mishra, Deepanjan Paul…·Debojyoti Chakraborty

This paper demonstrates that Francisella novicida Cas9 (FnCas9) has high specificity and low off-target editing, enabling precise genome editing in mammalian cells.

102 citationstop 4%

humanexperimental assay

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