Meghali Aich

Adrenomedullin Restores Mitochondrial Bioenergetics and Rescues Interneuron Phenotypes in Human Models of 22q11.2 Deletion Syndrome

This study identifies mitochondrial dysfunction in 22q11.2DS interneurons and shows that Adrenomedullin rescues these defects through distinct signaling pathways.

TOBF1 modulates mouse embryonic stem cell fate through co-transcriptional regulation of alternative splicing

This study identifies TOBF1 as a regulator of alternative splicing in mouse embryonic stem cells, showing its role in maintaining stem cell identity through co-transcriptional mechanisms.

Rapid, accurate, nucleobase detection using FnCas9

FELUDA uses FnCas9 for rapid, accurate nucleobase detection and is implemented in a point-of-care diagnostic tool for SARS-CoV-2.

Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing

This paper demonstrates that Francisella novicida Cas9 (FnCas9) has high specificity and low off-target editing, enabling precise genome editing in mammalian cells.