Arpit Mishra

Linking candidate causal autoimmune variants to T cell networks using genetic and epigenetic screens in primary human T cells.

The paper identifies 545 expression-modulating variants in CD4+ T cells linked to autoimmune diseases and shows they regulate genes in a lymphocyte activation network.

An atlas of silencer elements for the human and mouse genomes

The paper identifies and characterizes silencer elements genome-wide in human and mouse genomes using computational methods and experimental validation.

Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing

This paper demonstrates that Francisella novicida Cas9 (FnCas9) has high specificity and low off-target editing, enabling precise genome editing in mammalian cells.