Author

Katarzyna Modrzynska

University of GlasgowORCID 0000-0002-0877-3564Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Research Focus:phylogenetics / evolution· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ellen BushelliD· 2 shared Oliver BillkeriD· 2 shared A. Roberts· 1 shared Ana RiveroiD· 1 shared Andrew B. TobiniD· 1 shared Andrew G. JamiesoniD· 1 shared Andrew J. C. RusselliD· 1 shared Andrew P. WatersiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Ellen BushellORCID

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Author profile →

3 papers

Recent·Most cited

Inhibition of PfCLK3 a master regulator of malaria parasite RNA-splicing provides the basis for a radical cure for malaria

Omar Janha, Niniola Olaniyan, Ka Diam Go, Saumya Sharma, Dario Beraldi, Andrew G. Jamieson, Zbynek Bozdech, Andrew B. Tobin, Katarzyna Modrzynska

This study shows that inhibiting PfCLK3 disrupts RNA-splicing in malaria parasites, affecting 1125 genes and providing a novel mechanism for a radical cure.

bioRxiv · Oct 7, 2025 · PreprintMolecular Biology

Regulators of male and female sexual development critical for transmission of a malaria parasite

Andrew J. C. Russell, Theo Sanderson, Ellen Bushell, Arthur M. Talman, Burcu Anar, Gareth Girling, Mirjam Hunziker, Robyn S. Kent, Julie S. Martin, Tom Metcalf, Ruddy Montandon, Vikash Pandey, Mercedes Pardo, A. Roberts, Claire P. Sayers, , Oliver Billker

The paper identifies ten genes critical for male and female sexual development in Plasmodium berghei and reveals a regulatory cascade governing gametogenesis.

Cell Host & Microbe · Jan 11, 2023Peer-reviewedGenomics

Complete avian malaria parasite genomes reveal features associated with lineage specific evolution in birds and mammals

Ulrike Böhme, Thomas D. Otto, James Anthony Cotton, Sascha Steinbiss, Mandy J Sanders, Samuel O. Oyola, Antoine Nicot, Sylvain Gandon, Kailash P. Patra, Colin Herd, Ellen Bushell, Katarzyna Modrzynska, Oliver Billker, Joseph Michael Vinetz, Ana Rivero, , Matthew Berriman

The paper reports the genome sequencing of two avian malaria parasites and identifies lineage-specific features associated with their evolution in birds and mammals.

Genome Research · Apr 1, 2018Peer-reviewedGenomics