Omar Janha

Febrile temperatures influence the transmission competence of mature Plasmodium falciparum gametocytes

This study examines how febrile temperatures affect the viability and transmissibility of Plasmodium falciparum gametocytes, showing that higher temperatures reduce their ability to infect mosquitoes.

Inhibition of PfCLK3 a master regulator of malaria parasite RNA-splicing provides the basis for a radical cure for malaria

This study shows that inhibiting PfCLK3 disrupts RNA-splicing in malaria parasites, affecting 1125 genes and providing a novel mechanism for a radical cure.

Validation of the protein kinase PfCLK3 as a multi-stage cross species malarial drug target

This study identifies PfCLK3 as a druggable target for malaria by showing its essential role in multiple parasite life stages across species.