Author

Dipanjali Sinha

Institute of Genomics and Integrative Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

Souvik MaitiiD· 3 shared Asgar Hussain AnsariiD· 2 shared Debojyoti ChakrabortyiD· 2 shared Deepanjan PauliD· 2 shared Manoj KumariD· 2 shared Meghali AichiD· 2 shared Mohd. Azhar· 2 shared Namrata Sharma· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Souvik MaitiORCID

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3 papers

Recent·Most cited

Anti-COVID-19 Activity of FDA Approved Drugs through RNA G-quadruplex Binding

Shuvra Shekhar Roy, Shalu Sharma, Zaigham Abbas Rizvi, Dipanjali Sinha, Divya Gupta, Mercy Rophina, Paras Sehgal, Srikanth Sadhu, Manas Ranjan Tripathy, Sweety Samal, Souvik Maiti, Vinod Scaria, Sridhar Sivasubbu, Amit Awasthi, Krishnan Harinivas Harshan, , Shantanu Chowdhury

This study identifies FDA-approved drugs that bind G-quadruplexes in SARS-CoV-2 genomes, showing significant inhibition of viral replication in hamsters and cell cultures comparable to Remdesivir.

bioRxiv · May 31, 2022 · PreprintMolecular Biology

Rapid, accurate, nucleobase detection using FnCas9

Mohd. Azhar, Rhythm Phutela, Manoj Kumar, Asgar Hussain Ansari, Riya Rauthan, Sneha Gulati, Namrata Sharma, Dipanjali Sinha, Saumya Sharma, Sunaina Singh, Sundaram Acharya, Sajal Sarkar, Deepanjan Paul, Poorti Kathpalia, Meghali Aich, , Souvik Maiti

FELUDA uses FnCas9 for rapid, accurate nucleobase detection and is implemented in a point-of-care diagnostic tool for SARS-CoV-2.

Biosensors and Bioelectronics · Apr 5, 2021Peer-reviewedGenetic & Genomic Medicine

Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing

Sundaram Acharya, Arpit Mishra, Deepanjan Paul, Asgar Hussain Ansari, Mohd. Azhar, Manoj Kumar, Riya Rauthan, Namrata Sharma, Meghali Aich, Dipanjali Sinha, Saumya Sharma, Shivani Jain, Arjun Ray, Suman Jain, Sivaprakash Ramalingam, , Debojyoti Chakraborty

This paper demonstrates that Francisella novicida Cas9 (FnCas9) has high specificity and low off-target editing, enabling precise genome editing in mammalian cells.

Proceedings of the National Academy of Sciences · Sep 30, 2019Peer-reviewedMolecular Biology