Author

Joshua E. Mayfield

University of California San DiegoORCID 0000-0002-5253-0084Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alan R. SaltieliD· 1 shared Alexander Curtis JonesiD· 1 shared Alexandra C. NewtoniD· 1 shared Amanda WilpitziD· 1 shared Bichen ZhangiD· 1 shared Brent D. AulstoniD· 1 shared Christina J. SigurdsoniD· 1 shared Daniel B. McClatchyiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Alan R. SaltielORCID

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2 papers

Recent·Most cited

ESCRT-0 regulates AMPA receptor currents and Ca2+- dependent signaling

Mahsa Pourhamzeh, Lara E. Dozier, Amanda Wilpitz, Yixing Du, Daniel B. McClatchy, Mariel Kristine B Micael, Joshua E. Mayfield, Stephen K. Gilmore-Hall, Josephina E Ronson, Katrin Soldau, Donald P. Pizzo, Brent D. Aulston, Erin E. Sullivan, Timothy F. Shay, Jin Wang, , Christina J. Sigurdson

This study shows that Hrs, an ESCRT-0 protein, modulates AMPA receptor currents and Ca2+-dependent signaling by sensing and responding to neuronal activity at synapses.

bioRxiv · Jun 24, 2026 · PreprintNeuroscience

FBP1 is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness

Li Gu, Yahui Zhu, Kosuke Watari, Maiya Lee, Junlai Liu, Sofia Perez, Melinda Thai, Joshua E. Mayfield, Bichen Zhang, Karina Cunha e Rocha, Fuming Li, Laura C. Kim, Alexander Curtis Jones, Igor H. Wierzbicki, Xiao Liu, , Michael Karin

The paper identifies FBP1 as a nonenzymatic regulator that inhibits AKT activation to prevent insulin hyperresponsiveness and associated liver pathologies.

bioRxiv · Mar 5, 2023 · PreprintMolecular Biology