Author

Haoyun Yang

Houston MethodistORCID 0000-0002-5307-5079Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Aaron D. GitleriD· 1 shared Adam BrineriD· 1 shared Alex S. HolehouseiD· 1 shared Andrew S. NorrisiD· 1 shared Borna NovakiD· 1 shared Catherine Stuart· 1 shared Chad W. JohnstoniD· 1 shared Ewan K.S. McRaeiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

Aaron D. GitlerORCID

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2 papers

Recent·Most cited

Lipoproteins modulate the uptake and biological functionof cationic cell-penetrating peptides across the animal lineage.

Sovanny R. Taylor, Temilade V. Oluwasesin, Muthu Raj Salaikumaran, Borna Novak, Adam Briner, Roshan Ailani, Pilar I. Andrade, Paulo L. Onuchic, Olivia M. S. Carmo, Garam Kım, Jacob A. Blum, Mason Galliver, Catherine Stuart, Nicolás Méndez, Vedant Patel, , Steven Boeynaems

This study identifies lipoprotein-mediated endocytosis as a conserved mechanism for cationic cell-penetrating peptides across animal lineages, showing it modulates their antimicrobial function.

bioRxiv · Aug 24, 2026 · PreprintCell Biology

Structural basis of nearest-neighbor cooperativity in the ring-shaped gene regulatory protein TRAP from protein engineering and cryo-EM

Weicheng Li, Haoyun Yang, Kye Stachowski, Andrew S. Norris, Katie Lichtenthal, Skyler L. Kelly, Paul Gollnick, Vicki Hopper Wysocki, Mark P. Foster

This study investigates nearest-neighbor cooperativity in TRAP by engineering dTRAP variants and using cryo-EM and thermodynamic analyses to reveal structural and thermodynamic mechanisms of ligand binding cooperativity.

Proceedings of the National Academy of Sciences · Dec 30, 2024Peer-reviewedBiophysics