Author

Marya Shanabrough

Yale UniversityORCID 0000-0002-5366-9846Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Tamás L. HorváthiD· 2 shared Akiko IwasakiiD· 1 shared Alisson ClemenceauiD· 1 shared Annsea ParkiD· 1 shared Ashley Kristant· 1 shared Bernardo StutziD· 1 shared Diego Y. GrinmaniD· 1 shared Eric SongiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Tamás L. HorváthORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer-Associated Hypercalcemia Signals Through the Hindbrain to cause Anorexia

Diego Y. Grinman, Farzin M. Takyar, Pamela Dann, Marya Shanabrough, Stacey Brown, Alisson Clemenceau, Julie R. Hens, Bernardo Stutz, Lewis A. Chodosh, Wenhan Chang, Gerald I. Shulman, Tamás L. Horváth, John J. Wysolmerski

This study shows that hypercalcemia from tumor-secreted PTHrP activates hindbrain circuits linked to anorexia, and blocking hypercalcemia prevents these effects.

Journal of bone oncology · Apr 1, 2024Peer-reviewedCancer Biology

LINE-1 activation in the cerebellum drives ataxia

Takehiro Takahashi, Milan Stoiljković, Eric Song, Xiao‐Bing Gao, Yuki Yasumoto, Eriko Kudo, Fernando Carvalho, Yong Kong, Annsea Park, Marya Shanabrough, Klara Szigeti‐Buck, Zhong-Wu Liu, Ashley Kristant, Yalan Zhang, Parker L. Sulkowski, , Akiko Iwasaki

This study shows that activation of young LINE-1 elements in the cerebellum causes ataxia by inducing DNA damage, inflammation, and neuronal dysfunction in mice.

Neuron · Sep 6, 2022Peer-reviewedNeuroscience