Edita Bulovaite

The paper discovers a new synaptic structure called the Honeycomb Synapse in the spinal cord, showing its vulnerability in ALS models.

The paper develops computational models to explain synaptic protein distribution patterns in neurons by integrating molecular transport and local synaptic demand mechanisms across different ages and cell types.

The paper introduces NanoSYNMAP to map synaptic nanoarchitecture across the mouse lifespan, revealing how molecular proximity shapes synapse diversity.

This study uses 3D super-resolution microscopy to analyze PSD95 nanoarchitecture in the mouse brain, revealing diffuse supercomplexes outside synapses and distinct subtypes within synapses.

The paper investigates the sequential replacement of PSD95 subunits in synaptic supercomplexes, finding that this process is slowest in the cortex where PSD95 has the longest lifetime.

This study shows sleep deprivation reduces excitatory synapse diversity in the cortex and hippocampus of mice, while maintaining total synapse density.

The paper quantifies PSD95 protein lifetime in mouse synapses across lifespan and brain regions, revealing distinct patterns linked to development, behavior, and aging.

The paper shows that synaptome remodelling in mice with Pax6 mutation restores normal developmental trajectory, reversing neurodevelopmental disorder symptoms.