Ilya Shamovsky

This study shows H-NS silences bacterial antiviral immunity by compacting chromatin, and its deletion enhances phage defense in E. coli.

This paper characterizes OLD, an abortive immunity protein, revealing its structure and activation mechanism in response to phage replication and DNA defects in RecBCD-compromised cells.

This study shows that cysteine restriction in mice causes rapid weight loss by depleting glutathione and coenzyme A, activating stress responses, and increasing lipolysis.

This study identifies persistent RNA polymerase II backtracking in human cells and shows its enrichment in genes involved in translation, replication, and development.

The paper identifies CedA as a general transcription factor in E. coli that stabilizes an open-promoter complex without contacting DNA and modulates gene expression under stress conditions.

The paper identifies YcjW as a transcription factor that enables alternative H2S production in E. coli lacking 3MST, enhancing antibiotic and oxidative stress tolerance.