Author

Xin Xu

ARC Centre of Excellence in Synthetic BiologyORCID 0000-0002-5644-5397Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xin Xu9 papers · National Institute of Environmental Health Sciences

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander C. CarpenteriD· 1 shared Alexander S. Beliaev· 1 shared Ali Jahanian· 1 shared Anh Phan· 1 shared Anthony R. BornemaniD· 1 shared Bingyin PengiD· 1 shared Briardo LlorenteiD· 1 shared Chengqiang WangiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

Alexander C. CarpenterORCID

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2 papers

Recent·Most cited

Evolutionary stabilisation of stressful metabolism via integrated biocomputing and essential-gene metabolic locking circuits

Zeyu Mike Lu, Craig P. Barry, Masahiro Tominaga, Anh Phan, Ali Jahanian, Thomas Collier, Nicholas A. Wendrick, Samuel Evans, Liam McDonnell, Gabriele A. Netzel, Tim McCubbin, Shana Sunny Jacob, Patrick A. da Roza, Xin Xu, Chengqiang Wang, , Bingyin Peng

The paper develops synthetic genetic circuits in yeast to stabilize metabolic stress from terpene production, showing that coupling essential genes to synthetic pathways improves strain stability.

bioRxiv · Oct 9, 2026 · PreprintSynthetic Biology

Laboratory evolution and polyploid SCRaMbLE reveal genomic plasticity to synthetic chromosome defects and rearrangements

Thomas C. Williams, Heinrich Kroukamp, Xin Xu, Elizabeth L. I. Wightman, Briardo Llorente, Anthony R. Borneman, Alexander C. Carpenter, Niël van Wyk, Monica I. Espinosa, Elizabeth L. Daniel, Roy S. K. Walker, Yizhi Cai, Helena K. M. Nevalainen, Natalie C. Curach, Ira W. Deveson, , Ian T. Paulsen

The paper debugs a synthetic yeast chromosome and uses laboratory evolution to identify genomic rearrangements that suppress growth defects caused by synthetic modifications.

bioRxiv · Jul 22, 2022 · PreprintSynthetic Biology