Otger Campàs

Tissue surface mechanics constrains proliferation-driven forces to guide mammalian body axis elongation

This study shows that mammalian body axis elongation is driven by a posterior actin cap that constrains cell proliferation forces, differing from other vertebrates.

Species-specific basal fluidization shapes early forebrain development

This study identifies basal fluidization in human neuroepithelia as a tissue-level mechanism driving forebrain expansion, distinct from other great apes and mice.

SpinePy enables automated 3D spatiotemporal quantification of multicellular in vitro systems

SpinePy provides a framework for 3D spatiotemporal quantification of multicellular systems by aligning data to dynamic internal coordinate systems, revealing patterning classes influenced by gastruloid volume.

Morphodynamics of tip growing cells

The paper develops a theoretical framework to model the dynamics of tip-growing cells by coupling vesicle exocytosis to wall mechanics.