Sandra Piquet

New histone deposition recruits the DNA methylation maintenance machinery at sites of DNA damage repair

The paper shows DNA methylation is largely maintained during UV damage repair through recruitment of DNMT1 and DNMT3A, driven by UHRF1 and repair endonucleases, and linked to histone dynamics and transcriptional response.

Non-canonical ATR signalling via NBS1 phosphorylation propagates fork slowing from stressed to unperturbed nuclear regions

The histone chaperone activity of SPT2 controls chromatin structure and function in Metazoa

This study identifies the role of SPT2 in chromatin structure and function across Metazoa, showing its importance in germline development and chromatin accessibility.

The histone chaperone FACT coordinates H2A.X-dependent signaling and repair of DNA damage

The paper shows that the histone chaperone FACT deposits new H2A.X at DNA damage sites, facilitating repair and chromatin remodeling through interactions with ANP32E.