Author

Ronnie Shapira‐Frommer

Sheba Medical CenterORCID 0000-0001-6170-080XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Merav CoheniD· 2 shared Yochai WolfiD· 2 shared Abraham NissaniiD· 1 shared Alice Raizman· 1 shared Alona Veinblat· 1 shared Amir AharoniiD· 1 shared Angel PorgadoriD· 1 shared Aseel Khateeb· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Merav CohenORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Spatially enforced engagement of PD-1⁺ T cells with AXL⁺ cells reprograms the tumor microenvironment and overcomes anti-PD-1 resistance

Ksenia M. Yegodayev, Gregory Perelman, Tamar Shami, Bar Kaufman, Danialle Raviv, Divyasree Marripati, Aseel Khateeb, Raz Ben-Uri, Oshrat Galibov-Levi, Idan Milo, Alice Raizman, Alona Veinblat, Abraham Nissani, Noam Zuri, Dinesh Babu Manikandan, , Moshe Elkabets

This study develops a bispecific antibody that enhances T-cell engagement with AXL+ cells, improving anti-PD-1 therapy efficacy in HNSCC by remodeling the tumor microenvironment.

bioRxiv · Oct 28, 2026 · PreprintCancer Biology

Decoy Antibodies Block Extracellular HSP70, Prevent Self Signaling and Inhibit Melanoma Cell Survival

Noam Ben-Shalom, Shivang Parikh, Lilach Abramovitz, Ron Yefet, Paulee Manich, Dafna Tussia-Cohen, Ori Moskowitz, Roma Parikh, Stav Melamed, Ksenia Polonsky, Sébastien Apcher, Tzachi Hagai, Merav Cohen, Yochai Wolf, Ronnie Shapira‐Frommer, , Natalia Tarnovitski Freund

This study identifies decoy antibodies targeting extracellular HSP70 on melanoma-derived melanosomes, which inhibit tumor growth and survival in preclinical models and correlate with clinical response to immunotherapy.

Cell Reports · Apr 22, 2026Peer-reviewedImmunology