BioengineeringbioRxivPreprint
High-fidelity enhanced AsCas12a knock-in mice for efficient multiplexed gene editing, disease modeling and orthogonal immunogenetics
DOI 10.1101/2024.03.14.585126
Author
Yale UniversityORCID 0000-0002-5823-2328Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
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Matthew B. Dong, Kaiyuan Tang, Xiaoyu Zhou…·Sidi Chen
The paper demonstrates efficient multiplexed gene editing in immune cells using Cas12a/Cpf1 knock-in mice and associated viral vectors.