Author

Hanbing Cao

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Kaiyuan TangiD· 2 shared Medha MajetyiD· 2 shared Shao‐Yu FangiD· 2 shared Sidi CheniD· 2 shared Xiaoyu ZhouiD· 2 shared Andre LevchenkoiD· 1 shared Andrew DuiD· 1 shared Cole W. Christopher· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Kaiyuan TangORCID

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2 papers

Recent·Most cited

Engineered CTLA-4 targeting chimeras for targeted protein degradation and immune synapse reprogramming

Ping Ren, Shao‐Yu Fang, 赵姝姝, Hanbing Cao, Kaiyuan Tang, Xingbo Shang, Cole W. Christopher, Yunfei Jiao, Medha Majety, Andre Levchenko, David B. Weiner, Sidi Chen, Xiaoyu Zhou

This paper introduces cTACs, synthetic molecules that degrade PD-L1 across immune and tumor cells, enhancing T cell activation and tumor suppression in vivo.

bioRxiv · Oct 2, 2026 · PreprintImmunology

Cas12a/Cpf1 knock-in mice enable efficient multiplexed immune cell engineering

Matthew B. Dong, Kaiyuan Tang, Xiaoyu Zhou, Johanna Shen, Krista Chen, Hyunu R. Kim, Jerry Zhou, Hanbing Cao, Erica Vandenbulcke, Yueqi Zhang, Ryan Dz-Wei Chow, Andrew Du, Kazushi Suzuki, Shao‐Yu Fang, Medha Majety, , Sidi Chen

The paper demonstrates efficient multiplexed gene editing in immune cells using Cas12a/Cpf1 knock-in mice and associated viral vectors.

bioRxiv · Mar 14, 2023 · PreprintGenetics