Author

Darian J. Santana

St. Jude Children's Research HospitalORCID 0000-0002-5847-8352Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adam C. AbrahamiD· 1 shared Ashraf S. IbrahimiD· 1 shared Bin XuiD· 1 shared Chad J JohnsoniD· 1 shared Christina A. CuomoiD· 1 shared David R. AndesiD· 1 shared Derek QuintanillaiD· 1 shared Eliciane Cevolani MattosiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

Adam C. AbrahamORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Candida auris skin colonization is mediated by Als4112 and interactions with host extracellular matrix proteins

Guolei Zhao, Jingwen Lyu, Natalia A. Veniaminova, Robert Żarnowski, Eliciane Cevolani Mattos, Chad J Johnson, Derek Quintanilla, Haley Hautau, LeeAnn A. Hold, Bin Xu, Juliet A. E. Anku, Steph S. Steltzer, Kaustav Das Gupta, Darian J. Santana, Ashraf S. Ibrahim, , Teresa R. O’Meara

This study identifies Als4112 as critical for Candida auris skin colonization and explores collagen coatings to prevent adherence.

bioRxiv · Feb 13, 2025 · PreprintMicrobiology

Mutations in TAC1B drive CDR1 and MDR1 expression and azole resistance in C. auris

Katherine S. Barker, Darian J. Santana, Qing Hua Zhang, Tracy L. Peters, Jeffrey M. Rybak, Joachim Morschhäuser, Christina A. Cuomo, Phillip David Rogers

This study shows that TAC1B mutations in C. auris increase fluconazole and triazole resistance by upregulating CDR1 and MDR1, with CDR1 being the main driver.

bioRxiv · Feb 11, 2025 · PreprintMicrobiology