Author

Eva Medina

Helmholtz Centre for Infection ResearchORCID 0000-0002-5935-3260Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

André FleißneriD· 1 shared Andreas J. MülleriD· 1 shared Birte Dowerg· 1 shared Christiane WolziD· 1 shared Connor S.R. JankowskiiD· 1 shared Cora Schwendele· 1 shared Elena A. Seiß· 1 shared Fangfang CheniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

André FleißnerORCID

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Author profile →

3 papers

Recent·Most cited

Engagement of S. aureus shifts the activation trajectory of neutrophils towards serial eating

Cora Schwendele, Elena A. Seiß, Jasmina Schroter, Marcel Suntrop, Yannick Prager, Jonas Amore, Salome Manuel, Eva Medina, Matthias Gunzer, Christiane Wolz, Stephan Fricke, Thomas Schüler, Andreas J. Müller

This study shows that neutrophil phagocytic activity in S. aureus infection is driven by prior pathogen encounters rather than tissue dwell time.

bioRxiv · Sep 15, 2026 · PreprintImmunology

Itaconate is metabolized to 2-hydroxymethylsuccinate through a CoA-independent degradation pathway in mitochondria

Fangfang Chen, Laura Hadam, Birte Dowerg, Vadim S. Korotkov, Connor S.R. Jankowski, Ulrike Beutling, Hanna F Willenbockel, Ulrike Brandt, Eva Medina, André Fleißner, Henrikus Garritsen, Michael Jarek, Raimo Franke, Thomas Weichhart, Mark Brönstrup, , Thekla Cordes

The paper identifies 2-hydroxymethylsuccinate as a product of itaconate metabolism via a CoA-independent pathway and shows tissue-specific degradation routes.

bioRxiv · Sep 29, 2025 · PreprintCell Biology

Chronic Staphylococcus aureus infection is cured by theory-driven therapy

Lito A. Papaxenopoulou, Gang Zhao, Sahamoddin Khailaie, Konstantinos Katsoulis‐Dimitriou, Ingo Schmitz, Eva Medina, Haralampos Hatzikirou, Michael Meyer‐Hermann

A theory-driven treatment using heat-killed S. aureus eradicates chronic infection, reduces MDSCs, and reverses T-cell dysfunction in mice.

bioRxiv · Jan 17, 2020 · PreprintSystems Biology