Lukas von Ziegler

The paper identifies miR-1229-3p as a human-specific microRNA that delays neuronal synaptogenesis by reducing mitochondrial metabolism.

This study investigates how repeated stress affects molecular responses in the mouse hippocampus, finding widespread habituation without new adaptive responses or baseline gene expression changes.

This paper introduces behavioral flow analysis to detect latent phenotypes in rodent behavior, improving statistical power and transferability across experiments.

The paper shows that noradrenaline release from the locus coeruleus regulates gene expression in the hippocampus via beta-adrenergic receptors, with astrocyte-specific genes as key targets.

This study shows that chronic adolescent stress increases exploratory behavior and hippocampal gene expression but does not affect acute stress responses in adult mice.

This study identifies compartment-specific gene expression changes during synaptic scaling in rat hippocampal neurons, revealing distinct regulatory mechanisms in somatic and process compartments.

This study characterizes the molecular changes in the mouse hippocampus during the acute stress response using multiomic profiling and identifies rapid resolution of molecular events within 4 hours.

This study uses optogenetics and fMRI to show that D1 and D2 MSNs in the striatum differentially activate brain regions beyond the basal ganglia, revealing complex functional interactions.

The paper reanalyzes TRAP-seq data on acute stress response in hippocampal neurons, finding limited translational changes and no effect of sex or early life stress.

This paper introduces a deep learning pipeline for tracking and classifying behaviors of interacting primates and mice in complex environments using video data.

This study uses chemogenetic activation of the locus coeruleus in mice combined with resting-state fMRI to show rapid changes in functional connectivity, particularly in salience and amygdala networks.