Christopher R. Lee

Amygdalostriatal transition zone neurons encode sustained cue responses to guide defensive behaviors

The paper identifies the amygdalostriatal transition zone (ASt) as a critical structure for encoding sustained cue responses that guide defensive behaviors.

Social isolation recruits amygdala-medial prefrontal cortex projections to escalate alcohol drinking in male mice

This study identifies a BLA-mPFC neural pathway through which social isolation increases alcohol drinking in male mice by altering prefrontal cortex activity.

Separable Dorsal Raphe Dopamine Projections Mimic the Facets of a Loneliness-like State

The paper identifies distinct roles of three DRN dopamine neuron projections in social behavior and affective states through optogenetic and electrophysiological experiments.

Social Exclusion Amplifies Behavioral Responses to Physical Pain via Insular Neuromodulation

This study shows social exclusion increases physical pain responses through insular neuromodulation in mice, with opposing endocannabinoid and oxytocin signaling.

Predicting Future Development of Stress-Induced Anhedonia From Cortical Dynamics and Facial Expression

The paper predicts stress-induced anhedonia by analyzing cortical dynamics and facial expressions in mice, showing that mPFC valence encoding and behavior can predict susceptibility.

Breakdown of spatial coding and neural synchronization in epilepsy

This study investigates spatial coding and neural synchronization in epilepsy using in vivo calcium imaging and network modeling, finding impaired spatial processing and desynchronized firing in epileptic mice.