Author

Swati Subramanian

Max Planck Institute for Multidisciplinary SciencesORCID 0000-0002-6003-3045Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew Octavian SasmitaiD· 2 shared Constanze DeppiD· 2 shared Gesine SaheriD· 2 shared Katharina Overhoff· 2 shared Klaus‐Armin NaveiD· 2 shared Lena SpiethiD· 2 shared Oliver WirthsiD· 2 shared Stefan A. BerghoffiD· 2 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Andrew Octavian SasmitaORCID

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2 papers

Recent·Most cited

Oligodendrocytes and neurons contribute to amyloid-β deposition in Alzheimer's disease

Andrew Octavian Sasmita, Constanze Depp, T. I. Nazarenko, Ting Sun, Sophie B. Siems, Erinne Cherisse Ong, Yakum Bertrand Nkeh, Carolin Böhler, Xuan Yu, Bastian Bues, Lisa Evangelista, Shuying Mao, Bárbara Morgado, Zoe Y. Wu, Torben Ruhwedel, , Klaus‐Armin Nave

The paper shows oligodendrocytes contribute to amyloid-β plaques in Alzheimer's disease, but neurons are required for plaque formation.

Nature Neuroscience · Aug 5, 2024Peer-reviewedNeuroscience

Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer's disease

Constanze Depp, Ting Sun, Andrew Octavian Sasmita, Lena Spieth, Stefan A. Berghoff, T. I. Nazarenko, Katharina Overhoff, Agnes A. Steixner-Kumar, Swati Subramanian, Sahab Arinrad, Torben Ruhwedel, Wiebke Möbius, Sandra Göbbels, Gesine Saher, Hauke B. Werner, , Klaus‐Armin Nave

This study shows that ageing-related myelin dysfunction drives amyloid-beta deposition in Alzheimer's disease mouse models, suggesting myelin integrity as an upstream risk factor.

Nature · May 31, 2023Peer-reviewedNeuroscience