Cancer BiologybioRxivPreprint
SPTBN2 promotes an immunosuppressive tumor microenvironment and cross-resistance to anti-cancer therapies
Quoc Thang Bui, Raghavendra Basavaraja, Mayura R. Dhamdhere…·Serge Yu. Fuchs
This study identifies SPTBN2 as a regulator of immunosuppressive tumor microenvironment and cross-resistance to therapies, showing its role in suppressing CAR T-cell efficacy.