Author

Hallgeir Rui

Medical College of WisconsinORCID 0000-0002-8778-261XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ágnes HolczbaueriD· 1 shared Alice Wang· 1 shared Andréa RauiD· 1 shared Ben Z. StangeriD· 1 shared Constantinos KoumenisiD· 1 shared Crystal S. ConniD· 1 shared Daniel P. BeitingiD· 1 shared Dénis LaloëiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Ágnes HolczbauerORCID

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2 papers

Recent·Most cited

SPTBN2 promotes an immunosuppressive tumor microenvironment and cross-resistance to anti-cancer therapies

Quoc Thang Bui, Raghavendra Basavaraja, Mayura R. Dhamdhere, Ágnes Holczbauer, Luca Paruzzo, Puneeth Guruprasad, Michael Scaglione, Yingying Tang, Yu Sun, Daniel P. Beiting, Erik Nash, Hossein Fazelinia, Lynn A. Spruce, Alice Wang, Kai Tan, , Serge Yu. Fuchs

This study identifies SPTBN2 as a regulator of immunosuppressive tumor microenvironment and cross-resistance to therapies, showing its role in suppressing CAR T-cell efficacy.

bioRxiv · Apr 1, 2026 · PreprintCancer Biology

Individualized multi-omic pathway deviation scores using multiple factor analysis

Andréa Rau, Regina Manansala, Michael J. Flister, Hallgeir Rui, Florence Jaffrézic, Dénis Laloë, Paul Livermore Auer

This paper introduces padma, a pathway-centric tool that quantifies individualized multi-omic deviations in cancer, correlating them with clinical outcomes in breast and lung cancer.

Biostatistics · Jun 30, 2020Peer-reviewedBioinformatics