Author

Erik Nash

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Lynn A. SpruceiD· 2 shared Ágnes HolczbaueriD· 1 shared Alice Wang· 1 shared Amita SehgaliD· 1 shared Ben Z. StangeriD· 1 shared Constantinos KoumenisiD· 1 shared Crystal S. ConniD· 1 shared Daniel P. BeitingiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetics

Lynn A. SpruceORCID

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2 papers

Recent·Most cited

Gut-derived serine protease reduces sleep but extends lifespan

Rebecca S. Moore, Richard Xiong, Erick Astacio, Julie A. Williams, Thomas G. Brooks, Gregory R. Grant, Joseph A. Stucynski, Houssein Fazelinia, Erik Nash, Lynn A. Spruce, Amita Sehgal

This study identifies a gut-derived serine protease that reduces sleep but extends lifespan in Drosophila by increasing peripheral ROS, suggesting a link between sleep reduction and stress adaptation.

bioRxiv · Jun 29, 2026 · PreprintGenetics

SPTBN2 promotes an immunosuppressive tumor microenvironment and cross-resistance to anti-cancer therapies

Quoc Thang Bui, Raghavendra Basavaraja, Mayura R. Dhamdhere, Ágnes Holczbauer, Luca Paruzzo, Puneeth Guruprasad, Michael Scaglione, Yingying Tang, Yu Sun, Daniel P. Beiting, Erik Nash, Hossein Fazelinia, Lynn A. Spruce, Alice Wang, Kai Tan, , Serge Yu. Fuchs

This study identifies SPTBN2 as a regulator of immunosuppressive tumor microenvironment and cross-resistance to therapies, showing its role in suppressing CAR T-cell efficacy.

bioRxiv · Apr 1, 2026 · PreprintCancer Biology