Diet- and metabolic state-dependent remodeling of the mouse brain lipidome
Adélaïde Bernard, Kevin Huynh, Jen Xin Fach, Hang Yi Woo, He Liu, Yingying Liu, Natalie A. Mellet, Peter Meikle, Brian G. Drew, Y. Wang
This study shows that the mouse brain lipidome changes with diet and metabolic state, particularly highlighting the impact of high-fat diets on lipid remodeling in the hypothalamus and brainstem.
bioRxiv · Mar 2, 2026 · PreprintPhysiology