Author

Katharina S. S. Götze

TUM KlinikumORCID 0000-0002-6276-8002Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Jennifer RivièreiD· 2 shared Alexander Schäffer· 1 shared Ali AzhdariniaiD· 1 shared Ambrine SahaliD· 1 shared Amelie MuthiD· 1 shared Angelique Schönefeld· 1 shared Annette Frank· 1 shared Annika Maria Dufour· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

Jennifer RivièreORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A platform of robust patient-derived leukemia models covering subgroups for which no cell lines exist

Binje Vick, Vindi Jurinović, Kristina Kuhbandner, Lena Lagally, Lisa Latzko, Chiara Arnreich, Gerulf Hänel, Amelie Muth, Maja Rothenberg‐Thurley, Annika Maria Dufour, Stephanie E. Schneider, Lesca Miriam Holdt, Liliana Mura, Fabian Klein, Annette Frank, , Irmela Jeremias

The paper develops patient-derived AML PDX models that replicate primary AML biology and include subgroups lacking existing models, showing reduced leukemia growth after long-term chemotherapy.

bioRxiv · Sep 26, 2025 · PreprintCancer Biology

Limitations of the radiotheranostic concept in neuroendocrine tumors due to lineage-dependent somatostatin receptor expression on hematopoietic stem and progenitor cells

Nghia Trong Nguyen, Yu Min, Jennifer Rivière, Mark van der Garde, Sukhen C. Ghosh, Laura M. Bartos, Matthias Brendel, Florian C. Bassermann, Ali Azhdarinia, Wolfgang Weber, Katharina S. S. Götze, Susanne Kossatz

This paper shows that hematopoietic stem and progenitor cells express somatostatin receptors, leading to unexpected toxicity from radiopharmaceuticals used in neuroendocrine tumors.

Theranostics · May 25, 2025Peer-reviewedCancer Biology

DNMT/G9a Complex Inhibition Uncovers Epigenetic Vulnerabilities and Induces IFN-Response in Acute Myeloid Leukemia

Angelique Schönefeld, Costanza Zanetti, Eric C. Schmitt, Kevin Woods, Ashley Westerback, Sidney M. Mitsch, Frank Rühle, Simge Kelekçi, Lisa Fol, Viral Shah, Miriam Sanchez-Saez, Sophia Thevissen, Alexander Schäffer, Ulrike Regina Schmits, Daniel Sasca, , Borhane Guezguez

This study shows that inhibiting the DNMT/G9a complex targets specific epigenetic vulnerabilities in AML, inducing an IFN response and improving therapeutic outcomes.

bioRxiv · Dec 11, 2024 · PreprintCancer Biology