Edward Chuang

The paper investigates how condensate material properties affect exopher cargo selection in neurons, finding that gel-like condensates are more efficiently recruited than liquid-like ones.

This paper identifies design principles for modifying Hsp104 to enhance its therapeutic potential by tuning its collaboration with Hsp70 and Hsp40.

The paper shows that mechanical uterine distention enhances exopher extrusion from proteostressed C. elegans neurons, linking mechanical force to extracellular vesicle production and neurodegenerative disease mechanisms.