Dirk Reinhold

IgLON5 autoimmune antibodies activate Tau via neuronal hyperactivity

This study shows that IgLON5 autoantibodies cause neuronal hyperactivity and Tau pathology by clustering cell surface proteins, linking them to neurodegeneration.

CD36 is a metabolic checkpoint for Th2 cell tissue residency during allergic airway inflammation

This study identifies CD36 as a metabolic checkpoint sustaining Th2 cell tissue residency in allergic asthma by regulating GATA3 and PPARγ expression and interactions with dendritic cells.

Neuropathic pain and distinct CASPR2 autoantibody IgG subclasses drive neuronal hyperexcitability

The paper investigates how CASPR2 autoantibody subclasses, particularly IgG4, affect neuronal excitability and potassium channel function in patients with neuropathic pain.

Plasma concentrations of anti-inflammatory cytokine TGF-β are associated with hippocampal structure related to explicit memory performance in older adults

The paper examines the association between plasma TGF-β1 levels and hippocampal structure in older adults, finding a positive correlation with memory performance.

Olfactory transmucosal SARS-CoV-2 invasion as port of Central Nervous System entry in COVID-19 patients

The paper investigates SARS-CoV-2 entry into the CNS via the olfactory mucosa in COVID-19 patients and demonstrates neurotropism and cerebral thromboembolism.