Mariana De Sa Tavares Russo

This paper shows that viral inhibition of the APC/C enhances replication by increasing nucleotide pools through stabilization of biosynthesis enzymes.

This study shows that EZH2 inhibition in TNBC causes metabolic stress, making cells more sensitive to glutaminase inhibitors.

This study shows that both mTOR activation and inhibition increase H3K27me3 through distinct mechanisms, and this epigenetic change correlates with the anti-proliferative effects of mTOR inhibitors.

This study shows that paclitaxel induces cADPR production via Sarm1, increasing intra-axonal calcium and causing axon degeneration, with cADPR antagonists preventing neuropathy without affecting chemotherapy efficacy.