Author

Brian G. Coon

Oklahoma Medical Research FoundationORCID 0000-0002-4516-0193Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Martin Alexander SchwartziD· 2 shared Alice NealiD· 1 shared Amaury M. R. GenoveseiD· 1 shared Anna Rataj· 1 shared Anna TuliakovaiD· 1 shared Boris Ν. KholodenkoiD· 1 shared Charmain F. JohnsoniD· 1 shared Christiana RuhrbergiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersDevelopmental Biology

Martin Alexander SchwartzORCID

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3 papers

Recent·Most cited

A transcriptional code controlling fluid shear stress-induced gene expression

Lucija Fleisinger, Susann Bruche, Hyewon Lim, Anna Rataj, Helena Rodriguez‐Caro, Amaury M. R. Genovese, Vinesh Vinayachandran, Svanhild Nornes, Dorota Szumska, Dhruv Gupta, Indrika Ratnayaka, Kira M. Chouliaras, Marek Giers, Simon James Conway, Alice Neal, , Sarah De Val

This paper identifies FSS-dependent enhancers for KLF2 and reveals an essential MEF2-TBP double motif in their regulation, demonstrating a specific mechanism for FSS-induced gene activation.

bioRxiv · Feb 6, 2026 · PreprintDevelopmental Biology

Endothelial RIPK3 minimizes organotypic inflammation and vascular permeability in ischemia-reperfusion injury

Charmain F. Johnson, Christopher M. Schafer, Kathryn Young Burge, Brian G. Coon, Hala Chaaban, Courtney T. Griffin

This study shows that endothelial RIPK3 reduces vascular permeability and inflammation in ischemia-reperfusion injury by regulating IL-6 secretion and adhesion molecule expression.

Arteriosclerosis Thrombosis and Vascular Biology · Oct 30, 2025Peer-reviewedPathology

Angiogenic Signaling Counteracts Shear Stress-driven Arterial Patterning.

Dongying Chen, Oleksii S. Rukhlenko, Divyesh Joshi, Martina Rudnicki, Brian G. Coon, Raja Chakraborty, Anna Tuliakova, Elena Ioannou, Kathleen A. Martin, Boris Ν. Kholodenko, Christiana Ruhrberg, Martin Alexander Schwartz, Michael Simons

This study shows VEGF inhibits arterial specification in capillaries by suppressing Sox17, preventing premature arterialization driven by shear stress.

bioRxiv · Jan 23, 2024 · PreprintDevelopmental Biology