Snigdha Srivastava

This study identifies a cerebellar-midbrain pathway that selectively gates social vocalizations and demonstrates that targeted neuromodulation can restore vocal behavior without improving motor coordination.

This study shows common AAV vectors transduce multiple human brain cell types in organotypic slices, with astrocytes showing the most protein expression, and introduces a pipeline for optimizing AAV vectors.

This paper develops an in vitro model to study human retinal ganglion cell (RGC) connectivity with specific brain regions, showing that cultured RGCs form region-specific synapses with mouse brain targets.

The paper evaluates the transcriptional stability of cell types in ex vivo human brain tissue cultures over 14 days using single-nucleus RNA sequencing.

The paper identifies hybrid cells in human glioma with both neuronal and glial electrophysiological and transcriptomic features using Patch-sequencing and a new computational tool.