Qiongyi Zhao

The paper identifies C/D box snoRNAs, including orphans, that are involved in fear-related memory processes in mice by modulating mRNA methylation and synaptic function.

This study identifies latent regulatory programs from disease-associated variants to reveal biological mechanisms and clinical subtypes in complex diseases.

This study identifies Vaultrc5 as a noncoding RNA that regulates synaptic vault trafficking and RNA cargo dynamics, impacting learning and memory.

This study compares sixteen iPSC-CM differentiation protocols to identify how protocol-dependent cell states affect disease modeling capacity for cardiovascular conditions.

This study shows that early-life stress induces memory deficits by altering the m6A RNA epitranscriptome through FTO downregulation, affecting protein synthesis.

The paper identifies local translation of circular RNAs in the prefrontal cortex of mice, revealing a micropeptide involved in synaptic activity and memory.

The paper identifies a brain-enriched extrachromosomal circular DNA (ecDNA) that regulates plasticity-related genes and is linked to fear memory stability in mice.

The paper integrates multi-omic data from mouse and human prefrontal cortex subregions to identify cell-type-specific PTSD risk factors and regulatory landscapes.

starTracer improves marker gene identification in single-cell RNA-seq by enhancing specificity and speed compared to Seurat.

This paper introduces a consensus clustering method to identify robust signals from high-throughput screens by analyzing multi-scale data organization in cancer cell lines and bacterium models.

The paper shows DNA G-quadruplex regulates gene expression in neurons, affecting memory formation and fear extinction.

The paper identifies a lncRNA, Gas5, involved in fear extinction by regulating RNA granule trafficking and clustering at synapses in mice.

The paper compares optogenetic and pharmacological induction of sleep in Drosophila, finding they activate distinct transcriptional programs.

The paper creates an iPSC differentiation atlas and identifies TMEM88 as a regulator of mesendodermal development and blood pressure.

The paper shows that inhibiting circRNA Cdr1as in the infralimbic prefrontal cortex of mice impairs fear extinction memory.

The paper identifies synapse-specific m6A RNA readers and their role in fear extinction memory consolidation through RNA immunoprecipitation and sequencing in mice.

The paper identifies ADRAM, an experience-dependent lncRNA that interacts with 14-3-3 to regulate Nr4a2 expression and fear extinction memory in mice.

This study examines SFPQ dysregulation in ALS patients, finding increased intron retention, reduced mRNA expression in motor cortex, and cytoplasmic aggregates.

This study shows ADAR1 interacts with Z-DNA during fear extinction learning, affecting RNA editing and memory flexibility.

This study shows that m6dA accumulation in DNA of prefrontal cortical neurons is linked to fear extinction learning and gene expression.

This study shows that ING1 regulates activity-induced gene expression in cortical neurons by interacting with other epigenetic factors and affecting synaptic plasticity-related genes.

This study compares three differential expression analysis tools for RNA-Seq data, finding edgeR slightly outperforms others in true positives but may introduce more false positives.