Author

Laura Batlle‐Morera

Centre for Genomic RegulationORCID 0000-0002-6924-9002Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna BigasiD· 1 shared Anna Vert· 1 shared Avencia Sánchez-MejíasiD· 1 shared Daniel Alvarez VillanuevaiD· 1 shared Gourisankar GhoshiD· 1 shared Irene PecharromániD· 1 shared Isabel Turpín· 1 shared Joan BertraniD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Anna BigasORCID

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2 papers

Recent·Most cited

Synergic homology directed recombination by PRDM9 meiotic factor

Marta Sanvicente-García, Lourdes González-Bermúdez, Isabel Turpín, Laura Batlle‐Morera, Sandra Acosta, Marc Güell, Avencia Sánchez-Mejías

This study enhances homology-directed repair (HDR) efficiency by using PRDM9-Cas9 fusion with CtIP, validated through reporter systems for small and longer edits.

bioRxiv · Dec 5, 2022 · PreprintSynthetic Biology

Dynamic association of IκBα to chromatin is regulated by acetylation and cleavage of histone H4

Laura Marruecos, Joan Bertran, Daniel Alvarez Villanueva, María Carmen Mulero, Yolanda Guillén, Luis G Palma, Martin Floor, Anna Vert, Sara Arce‐Gallego, Irene Pecharromán, Laura Batlle‐Morera, Jordi Villà-Freixa, Gourisankar Ghosh, Anna Bigas, Lluı́s Espinosa

The paper shows that phosphorylated IκB binds chromatin via acetylated H4 and that proteolytic cleavage of H4 inhibits this binding, affecting intestinal cell differentiation.

EMBO Reports · Jul 5, 2021Peer-reviewedMolecular Biology