Author

Ulrike Engel

Heidelberg UniversityORCID 0000-0002-6953-6845Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Michael BoutrosiD· 2 shared A. Alshatwi Ali· 1 shared Ana Martín-VillalbaiD· 1 shared Andrea Sarvari· 1 shared Antonia SchubertiD· 1 shared Axel Carbone· 1 shared Barbara A. SchmittiD· 1 shared Christian ScheederiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

Michael BoutrosORCID

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Author profile →

3 papers

Recent·Most cited

Inflammatory injury drives CIN and STING loss in polyploidpancreatic acinar cells

Jan Brunken, Enrico Frigoli, A. Alshatwi Ali, Veronika Lummer, Axel Carbone, Andrea Sarvari, Sefa Berkay Cayir, Sanzhar Aitbay, Daria Kocherhina, Sonja Anslinger, Katharina Bauer, Ulrike Engel, Jan‐Philipp Mallm, Eli Pikarsky, Simon Anders, , Ana Martín-Villalba

The paper shows that inflammatory injury leads to polyploid pancreatic acinar cells with CIN and STING loss, contributing to tissue repair and cancer risk.

bioRxiv · Feb 11, 2026 · PreprintCell Biology

Shape stabilization in budding intestinal organoids by geometrical ratcheting

Oliver M. Drozdowski, Kim E. Boonekamp, Ulrike Engel, Michael Boutros, Ulrich S. Schwarz

This study uses 3D reconstructions and simulations to show that geometrical ratcheting stabilizes the shape of budding intestinal organoids through changes in tension and actomyosin reorganization.

bioRxiv · Apr 2, 2025 · PreprintBiophysics

Image-based screens identify regulators of endogenous Dvl2 biomolecular condensates

Antonia Schubert, Florian Heigwer, Christian Scheeder, Oksana Voloshanenko, Dominique Kranz, Franziska Ragaller, Nadine Winkler, Thilo Miersch, Barbara A. Schmitt, Melanie Kuhse, Daniel Gimenes, Diana Ordoñez‐Rueda, Jennifer Schwarz, Frank Stein, Dirk Jäger, , Michael Boutros

The paper identifies regulators of Dvl2 biomolecular condensates using image-based screens and phosphoproteomics, finding CK1δ/ε inhibition blocks condensate formation and modulates Wnt signaling.

bioRxiv · Jan 11, 2025 · PreprintCell Biology