Author

Michelle Tang

Duke UniversityORCID 0000-0002-6975-4607Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Michelle Tang1 paper · University of California San Diego

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Adam Q. BaueriD· 1 shared Aishwarya C. Ballapuram· 1 shared Aleksandra Bankovacki· 1 shared Andrew Ian WebbiD· 1 shared Asher J. AlbertsoniD· 1 shared Benjamin F. CravattiD· 1 shared Benjamin J. HuangiD· 1 shared Boer Xie· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperNeuroscience

Adam Q. BauerORCID

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3 papers

Recent·Most cited

In vivo validation of the palmitoylation cycle as a therapeutic target in NRAS-mutant cancer

Matthew Decker, Benjamin J. Huang, Timothy B. Ware, Christopher D. Boone, Michelle Tang, Julia Ybarra, Matthew J. Sale, Rony A. Francois, Aishwarya C. Ballapuram, Katrine A. Taran, Esteban Tarazona-Guzman, Pan-Yu Chen, Marcos Armendariz, Camille J. Leung, Max Harris, , Kevin Shannon

This study validates the palmitoylation cycle as a therapeutic target in NRAS-mutant cancers by showing that inhibiting ABHD17 reduces tumor growth and synergizes with MEK inhibitors.

bioRxiv · Mar 20, 2025 · PreprintCancer Biology

Normal Aging in Mice is Associated with a Global Reduction in Cortical Spectral Power and Network-Specific Declines in Functional Connectivity

Asher J. Albertson, Eric C. Landsness, Michelle Tang, Ping Yan, Hanyang Miao, Zachary P. Rosenthal, Byungchan Kim, Joseph P. Culver, Adam Q. Bauer, Jin‐Moo Lee

This study shows that aging in mice leads to reduced cortical spectral power and specific declines in functional connectivity in certain brain networks.

NeuroImage · May 17, 2022Peer-reviewedNeuroscience

Oligomerization-driven MLKL ubiquitylation antagonises necroptosis

Zikou Liu, Laura F. Dagley, Kristy Shield‐Artin, Samuel N. Young, Aleksandra Bankovacki, Xiangyi S. Wang, Michelle Tang, Jason A. Howitt, Che A. Stafford, Ueli Nachbur, Cheree Fitzgibbon, Sarah E. Garnish, Andrew Ian Webb, David Komander, James M. Murphy, , John Silke

This study demonstrates that MLKL ubiquitylation, triggered by oligomerization, regulates necroptosis by modulating MLKL activity and turnover.

bioRxiv · May 1, 2021 · PreprintMolecular Biology