Adam Q. Bauer

Normal Aging Limits Cortical Network Reorganization and Behavioral Recovery after Experimental Stroke

This study shows that aging impairs cortical network reorganization and behavioral recovery after stroke in mice, with young mice recovering despite persistent network degradation.

Psychedelic 5-HT2A receptor agonism: neuronal signatures and altered neurovascular coupling.

This study investigates the effects of the psychedelic 5-HT2A receptor agonist DOI on neuronal activity, hemodynamics, and neurovascular coupling in mice using wide-field optical imaging.

Arousal as a universal embedding for spatiotemporal brain dynamics

The paper demonstrates that a single arousal measurement can reconstruct spatiotemporal brain dynamics across multiple modalities in awake mice.

Concurrent optogenetic motor mapping of multiple limbs in awake mice reveals cortical organization of coordinated movements

This paper develops MOMM to map motor movement representations of multiple limbs in awake mice and finds cortical topographies for coordinated movements.

Homotopic contralesional excitation suppresses spontaneous circuit repair and global network reconnections following ischemic stroke

This study shows that contralesional excitation after stroke impairs local and global circuit reconnections by suppressing neuroplasticity-related genes.

Normal Aging in Mice is Associated with a Global Reduction in Cortical Spectral Power and Network-Specific Declines in Functional Connectivity

This study shows that aging in mice leads to reduced cortical spectral power and specific declines in functional connectivity in certain brain networks.

Sulfonylureas target the neurovascular response to decrease Alzheimer's pathology

This study shows that sulfonylureas reduce Alzheimer's pathology by targeting vascular KATP channels, decreasing amyloid-beta aggregation and improving vascular function in mice.

Transient uterine hypercontractility causes fetal cerebral oxidative stress and enduring mitochondrial and behavioral abnormalities in adolescent male rat offspring

This study shows that transient placental ischemia-hypoxemia in pregnant rats causes oxidative stress and long-term mitochondrial and behavioral issues in male offspring.