Author

Sofie Thys

University of AntwerpORCID 0000-0002-7080-3592Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Winnok Harald De VosiD· 2 shared Ann Van EeckhautiD· 1 shared Balázs GaszneriD· 1 shared Baukje BijnensiD· 1 shared Beatrice VitaliiD· 1 shared Camille Nina AllonsiusiD· 1 shared Carola ParoliniD· 1 shared Caroline E. M. K. DricotiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersNeuroscience

Winnok Harald De VosORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Exopolysaccharides of Lactobacillus crispatus mediate key balancing interactions with the vaginal mucosa

Vanessa Croatti, Caroline E. M. K. Dricot, Tom Eilers, Jelle Dillen, Tim Van Rillaer, Eline Cauwenberghs, Ilke Van Tente, Sam Bakelants, Dieter Vandenheuvel, Camille Nina Allonsius, Isabel Pintelon, Sofie Thys, Wendy Mensah, Marina Naldi, Peter A. Bron, , Sarah Lebeer

This study identifies exopolysaccharides (EPS) from Lactobacillus crispatus as critical for modulating immune responses in the vaginal mucosa, with EPS disruption leading to pro-inflammatory effects.

npj Biofilms and Microbiomes · Feb 19, 2026Peer-reviewedMicrobiology

S100A8-enriched microglia populate the brain of tau-seeded and accelerated aging mice

Roxane Gruel, Baukje Bijnens, Johanna Van Den Daele, Sofie Thys, Roland Willems, Dirk Wuyts, Debby Van Dam, Peter Verstraelen, Rosanne Verboven, Jana Roels, Niels Vandamme, Renzo Mancuso, Juan D. Pita‐Almenar, Winnok Harald De Vos

The paper identifies S100A8-enriched microglia in tauopathy and accelerated aging mouse models, showing their presence in human AD and tauopathy biopsies.

Aging Cell · Feb 25, 2024Peer-reviewedNeuroscience

Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells

Mireia Medrano, Wissal Allaoui, Mathias Van Bulck, Sofie Thys, Leila Makrini, Eve Seuntjens, Winnok Harald De Vos, Emmanuel Valjent, Balázs Gaszner, Ann Van Eeckhaut, Ilse Julia Smolders, Dimitri De Bundel

The paper characterizes NMU-expressing neurons in the adult mouse brain using a Nmu-Cre knock-in model, revealing a midline modulatory circuit centered on the VMH.

Open Biology · Jun 1, 2023Peer-reviewedNeuroscience