Joanne Edwards

Glandular architecture and malignant behaviour in colorectal cancer is regulated by the sialomucin Podocalyxin.

This study identifies Podocalyxin as a regulator of glandular architecture in colorectal cancer, showing its role in promoting tumour growth and metastasis.

Self-Supervised AI Reveals a Hidden Landscape of Prognostic Spatial Patterns in Multiplex Immunofluorescence Images

This paper introduces a self-supervised learning framework to analyze multiplex immunofluorescence images, revealing novel prognostic spatial patterns in cancer tissues.

Epithelial Plasticity and an Immune Suppressive Microenvironment Underpin Tumour Budding in Colorectal Cancer

This study identifies TNF- and TGF-β signaling as drivers of tumour budding in CRC, linked to poor prognosis and an immunosuppressive microenvironment.

Non-gonadal PIWI protein, Aubergine, regulates regenerative stem cell proliferation and tumourigenesis in the Drosophila adult intestine.

This study shows Aubergine regulates ISC proliferation and tumourigenesis in Drosophila intestine through protein synthesis, independent of its piRNA function.