Author
Cancer Research UK Scotland InstituteORCID 0000-0002-7055-2615Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Erin M. Cumming, Kai Rakovic, Kathryn A.F. Pennel…·David M. Bryant
This study identifies Podocalyxin as a regulator of glandular architecture in colorectal cancer, showing its role in promoting tumour growth and metastasis.
Frédéric Fercoq, Gemma S. Cairns, Victoria Louise Bridgeman…·Leo M. Carlin
This study shows that integrin conformation-dependent neutrophil slowing in pre-metastatic lungs obstructs capillaries and may contribute to immunosuppression in breast cancer.
Kathy McLay, Mathias Tesson, Louise R. Dutton…·JL Birch
This study shows that radiotherapy promotes lung metastasis in PDAC by increasing MRCK activity, which can be inhibited by BDP9066.
Luis Pardo, Madeleine Moore, Ruhi S. Deshmukh…·Jim C. Norman
This study shows that increased mRNA translation delays lung adenocarcinoma initiation and creates a vulnerability to MEK inhibitors in KRAS-driven tumors.
Sergi Marco, Peter J. Walsh, Alexey S. Revenko…·Jim C. Norman
This study identifies a mechanism by which antisense oligonucleotides (ASOs) enter cells via scavenger receptors and EPHA2-mediated trafficking to reach nuclear-adjacent endosomes, enhancing their effectiveness.