Author

Zeno Lavagnino

IFOMORCID 0000-0002-7247-8084Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:protein sequence· 1

Frequent Co-Authors

Andreas E. MooriD· 1 shared Andromachi KarakatsaniiD· 1 shared Angela BachiiD· 1 shared Arta AjaziiD· 1 shared Benjamin J. HersheyiD· 1 shared Dario ParazzoliiD· 1 shared David W. PistoniD· 1 shared Davide MazzaiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Andreas E. MoorORCID

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2 papers

Recent·Most cited

Compressive stress couples calcium signalling to translational control and proteostasis

Giuseppe Fragale, Benjamin J. Hershey, Yuwei Li, Giorgia Parodi, Galina V. Beznoussenko, Elisa Allievi, Arta Ajazi, Nicol Berti, Wanxin Zheng, Zeno Lavagnino, Vittoria Matafora, Federica Pisati, Nicola Manfrini, Stefano Biffo, Ligia Martinez, , Kristina M. Havas

This study shows compressive stress activates a calcium-dependent pathway that reduces translation and proteostasis through multiple mechanisms, correlating with poor survival in pancreatic cancer.

bioRxiv · Oct 9, 2026 · PreprintCell Biology

Short translational ramp determines efficiency of protein synthesis

Manasvi Verma, Junhong Choi, Kyle A. Cottrell, Zeno Lavagnino, Erica N. Thomas, Slavica Pavlovic‐Djuranovic, Paweł Szczęsny, David W. Piston, Hani S. Zaher, Joseph Daniel Puglisi, Sergej Djuranović

The paper shows that a short translational ramp in mRNA's first 5 codons significantly affects protein synthesis efficiency, independent of tRNA abundance or initiation efficiency.

Nature Communications · Dec 18, 2019Peer-reviewedMolecular Biology